. The schedule includes the opponents, dates, and results. The 49ers have many decisions to make in 2025 after missing the playoffs for the first time since 2020.

The san francisco 49ers’ week 17 loss to the detroit lions officially locked the team into last place in the nfc west, regardless of the outcome of their week 18 matchup against the. On nbc sports bay area’s “49ers game plan,” san francisco coach kyle shanahan expressed his desire for the 49ers to play spoiler in their week 17 matchup with the.